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DDR1 抗体 (pTyr513)

This anti-DDR1 antibody is a 兔 多克隆 antibody detecting DDR1 in WB, ELISA 和 IHC (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7213284
发货至: 中国

Quick Overview for DDR1 抗体 (pTyr513) (ABIN7213284)

抗原

See all DDR1 抗体
DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

适用

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人, 大鼠, 小鼠

宿主

  • 89
  • 26
  • 5

克隆类型

  • 87
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多克隆

标记

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This DDR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pTyr513

    原理

    DDR1 (phospho Tyr513) Polyclonal Antibody

    特异性

    Phospho-DDR1 (Y513) Polyclonal Antibody detects endogenous levels of DDR1 protein only when phosphorylated at Y513.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human DDR1 Phospho-Tyr513

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

    别名

    DDR1

    背景

    Rabbit Anti-DDR1 (phospho Tyr513) Polyclonal Antibody,DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE, Epithelial discoidin domain-containing receptor 1, Epithelial discoidin domain receptor 1, CD167 antigen-like family member A, Cell adhesion kinase, Discoidin receptor tyrosine kinase, HGK2,Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism.Discoidin domain receptor tyrosine kinase 1 encoded by DDR1 belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for DDR1.,Epithelial discoidin domain-containing receptor 1

    分子量

    observerd band 110kDa

    基因ID

    780

    UniProt

    Q08345

    途径

    RTK signaling, Smooth Muscle Cell Migration
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