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Caspase 10 B/C (AA 400-480) 抗体

适用: 人 ELISA, IF, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7202026
发货至: 中国
  • 抗原
    Caspase 10 B/C
    抗原表位
    • 1
    • 1
    AA 400-480
    适用
    宿主
    • 2
    克隆类型
    • 2
    多克隆
    标记
    • 2
    非结合性
    应用范围
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Caspase-10 B/C Polyclonal Antibody
    特异性
    Caspase-10 B/C Polyclonal Antibody detects endogenous levels of Caspase-10 B/C protein.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    免疫原
    Synthesized peptide derived from the C-terminal region of human Caspase-10 B/C at AA range: 400-480
    亚型
    IgG
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
    说明

    Primary Antibody

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原
    Caspase 10 B/C
    别名
    Caspase-10 B/C
    背景
    Rabbit Anti-Caspase-10 B/C Polyclonal Antibody,ALPS2, apoptotic protease Mch-4, CASP-10, CASPA, caspase-10, FADD-like ICE2, FAS-associated death domain protein interleukin-1B-convert,CASP10 encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in CASP10 are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for CASP10.,Caspase-10
    分子量
    observerd band 60kDa
    基因ID
    843
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