BAX 抗体 (pSer184)
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北京 101111
Quick Overview for BAX 抗体 (pSer184) (ABIN7223848)
抗原
See all BAX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer184
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原理
- Bax (phospho Ser184) Polyclonal Antibody
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特异性
- Phospho-Bax (S184) Polyclonal Antibody detects endogenous levels of Bax protein only when phosphorylated at S184.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Bax Phospho-Ser184
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亚型
- IgG
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anti-BCL2-Associated X Protein (BAX) (AA 84-175) antibody
BAX 适用: 人, 小鼠, 大鼠, Pig, Cow, 兔, 小鸡, 斑马鱼 WB, ELISA, FACS, IP, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-100) antibodyBAX 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (N-Term) antibodyBAX 适用: 人, 小鼠, 大鼠, 猴, Pig, Cow, 兔, 小鸡, 犬, 绵羊, Hamster, 马, 豚鼠, Avian, Cat, 驴, 山羊 WB, IF 宿主: 山羊 Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-158) antibodyBAX 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) antibodyKD Validated BAX 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 25GB450 unconjugated Recombinant Antibody
anti-BCL2-Associated X Protein (BAX) (AA 1-192) antibodyBAX 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 1F5-1B7 unconjugated
anti-BCL2-Associated X Protein (BAX) antibodyBAX 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2D8H2 unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 13-160) antibodyBAX 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 4H9B11 unconjugated
anti-BCL2-Associated X Protein (BAX) antibodyBAX 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2G6B2 unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 19-33), (N-Term) antibodyBAX 适用: 人, 小鼠, 大鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- BAX (BCL2-Associated X Protein (BAX))
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别名
- Bax
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背景
- Rabbit Anti-Bax (phospho Ser184) Polyclonal Antibody,BAX, BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4,The protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for BAX.,Apoptosis regulator BAX
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基因ID
- 581
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UniProt
- Q07812
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途径
- p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
抗原
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