AXL 抗体 (pTyr691)
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北京 101111
Quick Overview for AXL 抗体 (pTyr691) (ABIN7223504)
抗原
See all AXL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr691
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原理
- Axl (phospho Tyr691) Polyclonal Antibody
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特异性
- Phospho-Axl (Y691) Polyclonal Antibody detects endogenous levels of Axl protein only when phosphorylated at Y691.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Axl Phospho-Tyr691
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- AXL (AXL Receptor tyrosine Kinase (AXL))
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别名
- Axl
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背景
- Rabbit Anti-Axl (phospho Tyr691) Polyclonal Antibody,AXL, UFO, Tyrosine-protein kinase receptor UFO, AXL oncogene,The protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). AXL may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of AXL.,Tyrosine-protein kinase receptor UFO
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基因ID
- 558
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UniProt
- P30530
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途径
- RTK signaling, Cellular Response to Molecule of Bacterial Origin
抗原
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