IGF1R 抗体
Quick Overview for IGF1R 抗体 (ABIN7193763)
抗原
See all IGF1R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- IGF1R Antibody
-
纯化方法
- Purified antibody
-
免疫原
- Purified recombinant fragment of human IGF1R (AA: extra(741-935)) expressed in E. Coli.
-
亚型
- IgG2a
-
-
-
-
应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
-
别名
- IGF1R
-
背景
-
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
-
分子量
- 154.8 kDa
-
UniProt
- P08069
-
途径
- RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
抗原
-