ITPR2 抗体
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- 抗原 See all ITPR2 抗体
- ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ITPR2 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of Human ITPR2
- 亚型
- IgG
- Top Product
- Discover our top product ITPR2 Primary Antibody
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- 应用备注
- ELISA:1:2000-1:10000, IHC:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))
- 别名
- ITPR2 (ITPR2 产品)
- 别名
- AI649341 antibody, InsP3R-2 antibody, InsP3R-5 antibody, Ip3r2 antibody, Itpr5 antibody, insP3R2 antibody, IP3R2 antibody, inositol 1,4,5-trisphosphate receptor type 2 antibody, inositol 1,4,5-triphosphate receptor 2 antibody, inositol 1,4,5-trisphosphate receptor, type 2 antibody, ITPR2 antibody, Itpr2 antibody
- 背景
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Background: Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
Aliases: 4 antibody, 5-trisphosphate receptor antibody, Inositol 1 4 5 trisphosphate receptor type 2 antibody, Inositol 1,4,5-trisphosphate receptor type 2 antibody, Inositol 145 trisphosphate receptor type 2 antibody, InsP3 R2 antibody, InsP3R2 antibody, IP3 R2 antibody, IP3 receptor antibody, IP3 receptor isoform 2 antibody, IP3R 2 antibody, IP3R2 antibody, ITPR 2 antibody, Itpr2 antibody, ITPR2_HUMAN antibody, Type 2 inositol 1 4 5 trisphosphate receptor antibody, Type 2 inositol 1 antibody, Type 2 inositol 145 trisphosphate receptor antibody, Type 2 InsP3 receptor antibody
- UniProt
- Q14571
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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