CKMT1A 抗体
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- 抗原 See all CKMT1A 抗体
- CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CKMT1A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of Human CKMT1A/CKMT1B
- 亚型
- IgG
- Top Product
- Discover our top product CKMT1A Primary Antibody
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- 应用备注
- ELISA:1:1000-1:5000, WB:1:1000-1:3000, IHC:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
- 别名
- CKMT1A (CKMT1A 产品)
- 别名
- CKMT1 antibody, Mt-CK antibody, ScCKmit antibody, UbCKmit antibody, mi-CK antibody, Ckmt1 antibody, CKMT1B antibody, Mia-CK antibody, U-MtCK antibody, creatine kinase, mitochondrial 1A antibody, creatine kinase U-type, mitochondrial-like antibody, creatine kinase, mitochondrial 1, ubiquitous antibody, creatine kinase U-type, mitochondrial antibody, CKMT1A antibody, LOC100228000 antibody, Ckmt1 antibody, LOC100725326 antibody
- 背景
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Background: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.
Aliases: Acidic-type mitochondrial creatine kinase antibody, CKMT antibody, CKMT1 antibody, CKMT1B antibody, Creatine kinase mitochondrial 1 (ubiquitous) antibody, Creatine kinase mitochondrial 1B antibody, Creatine kinase U type mitochondrial antibody, Creatine kinase U-type antibody, KCRU_HUMAN antibody, Mia-CK antibody, mitochondrial antibody, U-MtCK antibody, Ubiquitous mitochondrial creatine kinase antibody, UMTCK antibody
- UniProt
- P12532
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