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- 抗原 See all CABLES2 抗体
- CABLES2 (Cdk5 and Abl Enzyme Substrate 2 (CABLES2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CABLES2 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of Human CABLES2
- 亚型
- IgG
- Top Product
- Discover our top product CABLES2 Primary Antibody
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anti-Cdk5 and Abl Enzyme Substrate 2 (CABLES2) antibody
CABLES2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cdk5 and Abl Enzyme Substrate 2 (CABLES2) (Internal Region) antibodyCABLES2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cdk5 and Abl Enzyme Substrate 2 (CABLES2) antibodyCABLES2 适用: 人 WB, IF, IHC, IC 宿主: 兔 Polyclonal unconjugated
anti-Cdk5 and Abl Enzyme Substrate 2 (CABLES2) (AA 131-239) antibodyCABLES2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cdk5 and Abl Enzyme Substrate 2 (CABLES2) (AA 182-210) antibodyCABLES2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB45108 unconjugated
anti-Cdk5 and Abl Enzyme Substrate 2 (CABLES2) (AA 91-140) antibodyCABLES2 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- ELISA:1:1000-1:2000, IHC:1:25-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CABLES2 (Cdk5 and Abl Enzyme Substrate 2 (CABLES2))
- 别名
- CABLES2 (CABLES2 产品)
- 别名
- cables2 antibody, CABLES2 antibody, C20orf150 antibody, dJ908M14.2 antibody, ik3-2 antibody, Cdk5 and Abl enzyme substrate 2 antibody, CDK5 and Abl enzyme substrate 2 antibody, CABLES2 antibody, cables2 antibody, Cables2 antibody
- 背景
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Background: Cables2 (Cdk5 and ABL1 enzyme substrate 2), also known as Ik3-2, is a 478 amino acid ubiquitously expressed protein that has a C-terminal cyclin box-containing domain, making it a member of the cyclin protein superfamily. A related protein, Cables, forms a trimolecular complex with Cdk5 and c-Abl in vivo, enhances apoptosis induced by overexpression of p53 and may be a tumor suppressor, due to its chromosomal loss of heterozygosity that is found in certain cancers. Cables2 shares 78 % sequence similarity with Cables in the region of the cyclin box-containing domain and, in similar functionality, associates with Cdk3, Cdk5 and c-Abl. However, unlike its close relative, Cables2 also contains an N-terminal region that enhances not only p53-mediated cell death, but also p53-independent cell death. This characteristic suggests that the gene encoding Cables2 may also function as a tumor suppressor gene.
Aliases: CABLES2 antibody, C20orf150 antibody, CDK5 and ABL1 enzyme substrate 2 antibody, Interactor with CDK3 2 antibody, Ik3-2 antibody
- UniProt
- Q9BTV7
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