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- 抗原 See all CYP1B1 抗体
- CYP1B1 (Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CYP1B1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from C-terminal of Human CP1B1.
- 亚型
- IgG
- Top Product
- Discover our top product CYP1B1 Primary Antibody
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anti-Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) (AA 1-260) antibody
CYP1B1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) antibodyCYP1B1 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) (Internal Region) antibodyCYP1B1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) (Center) antibodyCYP1B1 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) (AA 255-480) antibodyCYP1B1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) (AA 374-516) antibodyCYP1B1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) antibodyCYP1B1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) (Middle Region) antibodyCYP1B1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) (AA 441-543) antibodyCYP1B1 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) antibodyCYP1B1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB:1:500-1:3000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CYP1B1 (Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))
- 别名
- CYP1B1 (CYP1B1 产品)
- 别名
- CP1B antibody, CYPIB1 antibody, GLC3A antibody, P4501B1 antibody, P4501b1 antibody, CYP1B1 antibody, CYP1B antibody, zgc:136223 antibody, cytochrome P450 family 1 subfamily B member 1 antibody, cytochrome P450, family 1, subfamily b, polypeptide 1 antibody, cytochrome P450, family 1, subfamily B, polypeptide 1 antibody, cytochrome P450 1B1 antibody, CYP1B1 antibody, Cyp1b1 antibody, cyp1b1 antibody, LOC100719054 antibody
- 背景
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Background: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, retinoid and xenobiotics. Preferentially oxidizes 17beta-estradiol to the carcinogenic 4-hydroxy derivative, and a variety of procarcinogenic compounds to their activated forms, including polycyclic aromatic hydrocarbons. Promotes angiogenesis by removing cellular oxygenation products, thereby decreasing oxidative stress, release of antiangiogenic factor THBS2, then allowing endothelial cells migration, cell adhesion and capillary morphogenesis. These changes are concommitant with the endothelial nitric oxide synthase activity and nitric oxide synthesis. Plays an important role in the regulation of perivascular cell proliferation, migration, and survival through modulation of the intracellular oxidative state and NF-kappa-B expression and/or activity, during angiogenesis. Contributes to oxidative homeostasis and ultrastructural organization and function of trabecular meshwork tissue through modulation of POSTN expression.
Sutter T.R., J. Biol. Chem. 269:13092-13099(1994).
Tang Y.M., J. Biol. Chem. 271:28324-28330(1996).
Gorry M.C., Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.Aliases: Aryl hydrocarbon hydroxylase antibody, CP1B antibody, CP1B1_HUMAN antibody, Cyp1b1 antibody, CYPIB1 antibody, Cytochrome P450 1B1 antibody, Cytochrome P450 family 1 subfamily B polypeptide 1 antibody, Cytochrome P450 subfamily I (dioxin inducible) polypeptide 1 (glaucoma 3 primary infantile) antibody, Flavoprotein linked monooxygenase antibody, GLC3A antibody, Microsomal monooxygenase antibody, P4501B1 antibody, Xenobiotic monooxygenase antibody
- UniProt
- Q16678
- 途径
- Steroid Hormone Biosynthesis
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