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IKBKG 抗体 (Ser85)

IKBKG 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7180028
发货至: 中国
  • 抗原 See all IKBKG 抗体
    IKBKG (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))
    抗原表位
    • 28
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    Ser85
    适用
    • 134
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    宿主
    • 120
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    克隆类型
    • 114
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    多克隆
    标记
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    This IKBKG antibody is un-conjugated
    应用范围
    • 86
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    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    交叉反应
    人, 小鼠
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized non-phosphopeptide derived from Human IKK-γ, around the phosphorylation site of serine 85 (Q-A-S(p)-Q-R).
    亚型
    IgG
    Top Product
    Discover our top product IKBKG Primary Antibody
  • 应用备注
    WB:1:500-1:3000, IF:1:100-1:500,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    IKBKG (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))
    别名
    IKBKG (IKBKG 产品)
    别名
    AMCBX1 antibody, FIP-3 antibody, FIP3 antibody, Fip3p antibody, IKK-gamma antibody, IP antibody, IP1 antibody, IP2 antibody, IPD2 antibody, NEMO antibody, ZC2HC9 antibody, 1110037D23Rik antibody, AI848108 antibody, AI851264 antibody, AW124339 antibody, IKK[g] antibody, Nemo antibody, nemo antibody, fj33c07 antibody, wu:fj33c07 antibody, zgc:113492 antibody, MGC97885 antibody, IKBKG antibody, IKBKG_1 antibody, IKBKG_2 antibody, CG16910 antibody, DmIKK-gamma antibody, DmIKKgamma antibody, Dmel\\CG16910 antibody, Dmikkgamma antibody, IKK antibody, IKK[[gamma]] antibody, IKKg antibody, IKKgamma antibody, KEY antibody, Kenny antibody, Key antibody, dIKK antibody, dIKK-gamma antibody, dmIKKgamma antibody, inhibitor of nuclear factor kappa B kinase subunit gamma antibody, inhibitor of kappaB kinase gamma antibody, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma antibody, inhibitor of nuclear factor kappa B kinase subunit gamma L homeolog antibody, kenny antibody, IKBKG antibody, Ikbkg antibody, ikbkg antibody, ikbkg.L antibody, IKBKG_1 antibody, key antibody
    背景

    Background: Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response, this function requires 'Lys-27'-linked polyubiquitination.

    Li Y., Proc. Natl. Acad. Sci. U.S.A. 96:1042-1047(1999).
    Jin D.-Y., J. Biomed. Sci. 6:115-120(1999).
    Rothwarf D.M., Nature 395:297-300(1998).

    Aliases: IkB kinase associated protein 1 antibody, IkB kinase subunit gamma antibody, Inhibitor of nuclear factor kappa B kinase subunit gamma antibody, AMCBX1 antibody, FIP 3 antibody, FIP-3 antibody, FIP3 antibody, Fip3p antibody, I kappa B kinase gamma antibody, I-kappa-B kinase subunit gamma antibody, IkB kinase gamma subunit antibody, IkB kinase subunit gamma antibody, IkB kinase-associated protein 1 antibody, Ikbkg antibody, IKK gamma antibody, IKK-gamma antibody, IKKAP1 antibody, IKKG antibody, IMD33 antibody, Incontinentia pigmenti antibody, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase gamma antibody, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase of, gamma antibody, Inhibitor of nuclear factor kappa-B kinase subunit gamma antibody, IP antibody, IP1 antibody, IP2 antibody, IPD2 antibody, NEMO antibody, NEMO_HUMAN antibody, NF kappa B essential modifier antibody, NF kappa B essential modulator antibody, NF-kappa-B essential modifier antibody, NF-kappa-B essential modulator antibody, ZC2HC9 antibody

    UniProt
    Q9Y6K9
    途径
    NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, M Phase, Production of Molecular Mediator of Immune Response, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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