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BAX 抗体 (Thr167)

This anti-BAX antibody is a 兔 多克隆 antibody detecting BAX in WB, ELISA 和 IF. Suitable for 人.
产品编号 ABIN7179980
发货至: 中国

Quick Overview for BAX 抗体 (Thr167) (ABIN7179980)

抗原

See all BAX 抗体
BAX (BCL2-Associated X Protein (BAX))

适用

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宿主

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克隆类型

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多克隆

标记

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This BAX antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    Thr167

    交叉反应

    人, 小鼠

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized non-phosphopeptide derived from Human Bax around the phosphorylation site of threonine 167 (F-G-T(p)-P-T).

    亚型

    IgG
  • 应用备注

    WB:1:500-1:3000, IF:1:100-1:500,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    BAX (BCL2-Associated X Protein (BAX))

    别名

    BAX

    背景

    Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

    Oltvai Z.N., Cell 74:609-619(1993).
    Cuddeback S.M., J. Biol. Chem. 276:20559-20565(2001).
    Guo B., Nature 423:456-461(2003)

    Aliases: Apoptosis regulator BAX antibody, BAX antibody, Bax-protein antibody, BAX_HUMAN antibody, BAXA antibody, Baxdelta2G9 antibody, Baxdelta2G9omega antibody, Baxdelta2omega antibody, Bcl-2-like protein 4 antibody, BCL2 associated X protein antibody, BCL2 associated X protein omega antibody, BCL2 associated X protein transcript variant delta2 antibody, Bcl2-L-4 antibody, BCL2L4 antibody, membrane isoform alpha antibody

    UniProt

    Q07812

    途径

    p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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