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BAX 抗体 (Thr167)

BAX 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7179980
发货至: 中国
  • 抗原 See all BAX 抗体
    BAX (BCL2-Associated X Protein (BAX))
    抗原表位
    • 32
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    Thr167
    适用
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    • 149
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    宿主
    • 149
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    克隆类型
    • 162
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    多克隆
    标记
    • 124
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    This BAX antibody is un-conjugated
    应用范围
    • 211
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    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    交叉反应
    人, 小鼠
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized non-phosphopeptide derived from Human Bax around the phosphorylation site of threonine 167 (F-G-T(p)-P-T).
    亚型
    IgG
    Top Product
    Discover our top product BAX Primary Antibody
  • 应用备注
    WB:1:500-1:3000, IF:1:100-1:500,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    BAX (BCL2-Associated X Protein (BAX))
    别名
    BAX (BAX 产品)
    背景

    Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

    Oltvai Z.N., Cell 74:609-619(1993).
    Cuddeback S.M., J. Biol. Chem. 276:20559-20565(2001).
    Guo B., Nature 423:456-461(2003)

    Aliases: Apoptosis regulator BAX antibody, BAX antibody, Bax-protein antibody, BAX_HUMAN antibody, BAXA antibody, Baxdelta2G9 antibody, Baxdelta2G9omega antibody, Baxdelta2omega antibody, Bcl-2-like protein 4 antibody, BCL2 associated X protein antibody, BCL2 associated X protein omega antibody, BCL2 associated X protein transcript variant delta2 antibody, Bcl2-L-4 antibody, BCL2L4 antibody, membrane isoform alpha antibody

    UniProt
    Q07812
    途径
    p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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