TNF alpha 抗体 (AA 78-234)
Quick Overview for TNF alpha 抗体 (AA 78-234) (ABIN7179334)
抗原
See all TNF alpha 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 78-234
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交叉反应
- 绵羊
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Sheep Tumor necrosis factor protein (78-234AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:1000-1:5000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
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别名
- TNF
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背景
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Background: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells
Aliases: TNF antibody, TNFA antibody, TNFSF2 antibody, Tumor necrosis factor antibody, Cachectin antibody, TNF-alpha antibody, Tumor necrosis factor ligand superfamily member 2 antibody, TNF-a) [Cleaved into: Tumor necrosis factor antibody, membrane form antibody, N-terminal fragment antibody, NTF), Intracellular domain 1 antibody, ICD1), Intracellular domain 2 antibody, ICD2), C-domain 1, C-domain 2, Tumor necrosis factor antibody, soluble form] antibody
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UniProt
- P23383
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途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
抗原
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