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Survivin 抗体 (AA 1-140)

This anti-Survivin antibody is a 兔 多克隆 antibody detecting Survivin in WB 和 ELISA. Suitable for 小鼠.
产品编号 ABIN7176985
发货至: 中国

Quick Overview for Survivin 抗体 (AA 1-140) (ABIN7176985)

抗原

See all Survivin (BIRC5) 抗体
Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

适用

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小鼠

宿主

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克隆类型

  • 93
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多克隆

标记

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This Survivin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 1-140

    交叉反应

    人, 小鼠

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Mouse Baculoviral IAP repeat-containing protein 5 protein (1-140AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:5000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

    别名

    Birc5

    背景

    Background: Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex, directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May counteract a default induction of apoptosis in G2/M phase. The acetylated form represses STAT3 transactivation of target gene promoters. May play a role in neoplasia. Inhibitor of CASP3 and CASP7.

    Aliases: Birc5 antibody, Api4 antibody, Iap4Baculoviral IAP repeat-containing protein 5 antibody, Apoptosis inhibitor 4 antibody, Apoptosis inhibitor survivin antibody, TIAP antibody

    UniProt

    O70201

    途径

    Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
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