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TRADD 抗体 (AA 1-312)

This anti-TRADD antibody is a 兔 多克隆 antibody detecting TRADD in WB, IHC, ELISA, IF 和 IP. Suitable for 人.
产品编号 ABIN7173904
发货至: 中国

Quick Overview for TRADD 抗体 (AA 1-312) (ABIN7173904)

抗原

See all TRADD 抗体
TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

适用

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宿主

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克隆类型

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多克隆

标记

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This TRADD antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
  • 抗原表位

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    AA 1-312

    交叉反应

    人, 大鼠

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Tumor necrosis factor receptor type 1-associated DEATH domain protein (1-312AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200, IP:1:200-1:2000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

    别名

    TRADD

    背景

    Background: The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.

    Aliases: 9130005N23Rik antibody, AA930854 antibody, TNFR1 associated DEATH domain protein antibody, TNFR1-associated DEATH domain protein antibody, TNFRSF1A associated via death domain antibody, TNFRSF1A-associated via death domain antibody, tradd antibody, TRADD_HUMAN antibody, Tumor necrosis factor receptor type 1 associated DEATH domain protein antibody, Tumor necrosis factor receptor type 1-associated DEATH domain protein antibody

    UniProt

    Q15628

    途径

    NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C
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