E2F1 抗体 (AA 133-362)
Quick Overview for E2F1 抗体 (AA 133-362) (ABIN7172513)
抗原
See all E2F1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 133-362
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交叉反应
- 人, 小鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Transcription factor E2F1 protein (133-362AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- E2F1 (E2F Transcription Factor 1 (E2F1))
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别名
- E2F1
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背景
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Background: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5\\\'-TTTC[CG]CGC-3\\\' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812).
Aliases: Dmel\CG6376 antibody, Dmel_CG6376 antibody, drosE2F1 antibody, E(Sev-CycE)3A antibody, E(var)3-93E antibody, E2-promoter binding facto antibody, E2F 1 antibody, E2F transcription factor 1 antibody, E2F-1 antibody, E2f-PA antibody, E2f-PB antibody, E2f-PC antibody, E2F1 antibody, E2f1 E2F transcription factor 1 antibody, E2F1_HUMAN antibody, Evar(3)164 antibody, KIAA4009 antibody, l(3)07172 antibody, l(3)j3B1 antibody, l(3)j3C2 antibody, l(3)rM729 antibody, mKIAA4009 antibody, OTTHUMP00000030661 antibody, PBR3 antibody, PRB binding protein E2F 1 antibody, PRB-binding protein E2F-1 antibody, RBAP 1 antibody, RBAP-1 antibody, RBAP1 antibody, RBBP-3 antibody, RBBP3 antibody, RBP 3 antibody, RBP3 antibody, Retinoblastoma-associated protein 1 antibody, Retinoblastoma-binding protein 3 antibody, Transcription factor E2F1 antibody
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UniProt
- Q01094
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途径
- p53 Pathway, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy
抗原
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