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TRAF3 抗体 (AA 1-40)

This anti-TRAF3 antibody is a 兔 多克隆 antibody detecting TRAF3 in WB, ELISA 和 IF. Suitable for 人.
产品编号 ABIN7172236
发货至: 中国

Quick Overview for TRAF3 抗体 (AA 1-40) (ABIN7172236)

抗原

See all TRAF3 抗体
TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

适用

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宿主

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克隆类型

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多克隆

标记

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This TRAF3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)
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    AA 1-40

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human TNF receptor-associated factor 3 protein (1-40AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:200-1:2000, IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

    别名

    TRAF3

    背景

    Background: Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon. Required for normal antibody isotype switching from IgM to IgG. Plays a role T-cell dependent immune responses. Plays a role in the regulation of antiviral responses. Is an essential constituent of several E3 ubiquitin-protein ligase complexes. May have E3 ubiquitin-protein ligase activity and promote \\\'Lys-63\\\'-linked ubiquitination of target proteins. Inhibits activation of NF-kappa-B in response to LTBR stimulation. Inhibits TRAF2-mediated activation of NF-kappa-B. Down-regulates proteolytic processing of NFKB2, and thereby inhibits non-canonical activation of NF-kappa-B. Promotes ubiquitination and proteasomal degradation of MAP3K14.

    Aliases: CAP 1 antibody, CAP-1 antibody, CAP1 antibody, CD40 associated protein 1 antibody, CD40 binding protein antibody, CD40 bp antibody, CD40 receptor associated factor 1 antibody, CD40 receptor-associated factor 1 antibody, CD40-binding protein antibody, CD40BP antibody, CRAF 1 antibody, CRAF1 antibody, IIAE5 antibody, LAP 1 antibody, LAP1 antibody, LMP1 associated protein antibody, LMP1-associated protein 1 antibody, MIPT3 antibody, TNF receptor associated factor 3 antibody, TNF receptor-associated factor 3 antibody, TRAF 3 antibody, Traf3 antibody, TRAF3_HUMAN antibody

    UniProt

    Q13114

    途径

    NF-kappaB Signaling, Apoptosis, TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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