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- 抗原 See all TGFBR2 抗体
- TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
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抗原表位
- AA 25-159
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TGFBR2 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human TGF-beta receptor type-2 protein (25-159AA)
- 亚型
- IgG
- Top Product
- Discover our top product TGFBR2 Primary Antibody
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anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 23-280) antibody
TGFBR2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 13-40), (N-Term) antibodyTGFBR2 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB31405 unconjugated
anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 241-330) antibodyTGFBR2 适用: 人, 小鼠, 大鼠, 兔, Cow WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) antibodyTGFBR2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 13-40) antibodyTGFBR2 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) antibodyTGFBR2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 62-165) antibodyTGFBR2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (pSer225), (pSer250) antibodyTGFBR2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (AA 209-590) antibodyTGFBR2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) (Tyr159) antibodyTGFBR2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
- 别名
- TGFBR2 (TGFBR2 产品)
- 别名
- AAT3 antibody, FAA3 antibody, LDS1B antibody, LDS2B antibody, MFS2 antibody, RIIC antibody, TAAD2 antibody, TGFR-2 antibody, TGFbeta-RII antibody, 1110020H15Rik antibody, AU042018 antibody, DNIIR antibody, RIIDN antibody, TBR-II antibody, TbetaR-II antibody, TbetaRII antibody, TGFBR2 antibody, TBETA-RII antibody, TGFBRII antibody, TGF-beta 2 antibody, Tgfbr2T antibody, cb537 antibody, tgfbr2 antibody, wu:fj05c10 antibody, zgc:110498 antibody, transforming growth factor beta receptor 2 antibody, transforming growth factor, beta receptor II antibody, transforming growth factor, beta receptor 2 antibody, transforming growth factor beta receptor 2b antibody, TGFBR2 antibody, Tgfbr2 antibody, tgfbr2b antibody
- 背景
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Background: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 Molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.
Aliases: AAT3 antibody, FAA3 antibody, LDS1B antibody, LDS2 antibody, LDS2B antibody, MFS2 antibody, RIIC antibody, TAAD2 antibody, TbetaR II antibody, TbetaR-II antibody, TGF beta receptor type 2 antibody, TGF beta receptor type II antibody, TGF beta receptor type IIB antibody, TGF beta type II receptor antibody, TGF-beta receptor type II antibody, TGF-beta receptor type-2 antibody, TGF-beta type II receptor antibody, TGF-beta-R2 antibody, TGFB R2 antibody, TGFbeta - RII antibody, TGFbeta RII antibody, Tgfbr2 antibody, TGFR-2 antibody, TGFR2_HUMAN antibody, Transforming growth factor beta receptor II antibody, Transforming growth factor beta receptor type II antibody, Transforming growth factor beta receptor type IIC antibody, Transforming growth factor, beta receptor II (70/80 kDa) antibody, transforming growth factor, beta receptor II alpha antibody, transforming growth factor, beta receptor II beta antibody, transforming growth factor, beta receptor II delta antibody, transforming growth factor, beta receptor II epsilon antibody, transforming growth factor, beta receptor II gamma antibody, Transforming growth factor-beta receptor type II antibody
- UniProt
- P37173
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