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SMARCE1 抗体 (AA 20-243) (FITC)

SMARCE1 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7171085
发货至: 中国
  • 抗原 See all SMARCE1 抗体
    SMARCE1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1))
    抗原表位
    • 15
    • 9
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 20-243
    适用
    • 61
    • 28
    • 23
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    宿主
    • 54
    • 6
    • 1
    克隆类型
    • 49
    • 12
    多克隆
    标记
    • 34
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SMARCE1 antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 protein (20-243AA)
    亚型
    IgG
    Top Product
    Discover our top product SMARCE1 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SMARCE1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1))
    别名
    SMARCE1 (SMARCE1 产品)
    别名
    BAF57 antibody, XBaf57 antibody, MGC52696 antibody, MGC69429 antibody, MGC81726 antibody, SMARCE1 antibody, DKFZp459O2235 antibody, fb54d11 antibody, wu:fb33d02 antibody, wu:fb54d11 antibody, Baf57 antibody, 2810417B20Rik antibody, 5830412H02Rik antibody, 9030408N19Rik antibody, Baf27 antibody, RGD1304726 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 L homeolog antibody, smarce1 antibody, SMARCE1 antibody, smarce1.L antibody, Smarce1 antibody
    背景

    Background: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Required for the coactivation of estrogen responsive promoters by Swi/Snf complexes and the SRC/p160 family of histone acetyltransferases (HATs). Also specifically interacts with the CoREST corepressor resulting in repression of neuronal specific gene promoters in non-neuronal cells.

    Aliases: BAF57 antibody, BRG1 associated factor 57 antibody, BRG1-associated factor 57 antibody, Chromatin remodeling complex BRG1 associated factor 57 antibody, FLJ35648 antibody, SMARCE 1 antibody, SMARCE1 antibody, SMCE1_HUMAN antibody, SWI/SNF related matrix associated actin dependent regulator of chromatin e1 antibody, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily e member 1 antibody, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 antibody

    UniProt
    Q969G3
    途径
    Chromatin Binding
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