SMARCB1 抗体 (AA 86-385)
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- 抗原 See all SMARCB1 抗体
- SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1))
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抗原表位
- AA 86-385
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SMARCB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 protein (86-385AA)
- 亚型
- IgG
- Top Product
- Discover our top product SMARCB1 Primary Antibody
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anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) (AA 81-180) antibody
SMARCB1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3E10 unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) antibodyKO Validated SMARCB1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) (AA 1-385) antibodySMARCB1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) (AA 1-385) antibodySMARCB1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) (AA 301-385) antibodySMARCB1 适用: 人, 小鼠 ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) antibodySMARCB1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) (AA 1-385) antibodySMARCB1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) (AA 81-180) antibodySMARCB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C4 unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) (AA 123-202) antibodySMARCB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D10 unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) antibodySMARCB1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1))
- 别名
- SMARCB1 (SMARCB1 产品)
- 别名
- SMARCB1 antibody, BAF47 antibody, INI1 antibody, MRD15 antibody, RDT antibody, RTPS1 antibody, SNF5 antibody, SNF5L1 antibody, Sfh1p antibody, Snr1 antibody, hSNFS antibody, AU020204 antibody, Baf47 antibody, Ini1 antibody, SNF5/INI1 antibody, Snf5 antibody, fc51b01 antibody, smarcb1 antibody, wu:fc51b01 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 S homeolog antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b antibody, SMARCB1 antibody, Smarcb1 antibody, smarcb1.S antibody, smarcb1b antibody
- 背景
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Background: Core component of the BAF (hSWI/SNF) complex. This ATP-dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal. This change in supercoiling would be due to the conversion of up to one-half of the nucleosomes on polynucleosomal arrays into asymmetric structures, termed altosomes, each composed of 2 histones octamers. Stimulates in vitro the remodeling activity of SMARCA4/BRG1/BAF190A. Involved in activation of CSF1 promoter. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Plays a key role in cell-cycle control and causes cell cycle arrest in G0/G1. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.
Aliases: BAF47 antibody, BRG1-associated factor 47 antibody, hSNF5 antibody, INI1 antibody, Integrase interactor 1 protein antibody, Malignant rhabdoid tumor suppressor antibody, RDT antibody, RTPS1 antibody, Sfh1p antibody, SMARCB1 antibody, SNF5 homolog antibody, SNF5_HUMAN antibody, SNF5L1 antibody, Snr1 antibody, Sucrose nonfermenting yeast homolog like 1 antibody, SWI/SNF complex component SNF5 antibody, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 antibody, SWI10 antibody, Transcription factor TYE4 antibody, Transcription regulatory protein SNF5 antibody, TYE4 antibody
- UniProt
- Q12824
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