SMARCC2 抗体 (AA 300-650)
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- 抗原 See all SMARCC2 抗体
- SMARCC2 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 2 (SMARCC2))
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抗原表位
- AA 300-650
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SMARCC2 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human SWI/SNF complex subunit SMARCC2 protein (300-650AA)
- 亚型
- IgG
- Top Product
- Discover our top product SMARCC2 Primary Antibody
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anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 2 (SMARCC2) (AA 150-250) antibody
SMARCC2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 2 (SMARCC2) antibodySMARCC2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 2 (SMARCC2) (AA 300-650) antibodySMARCC2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 2 (SMARCC2) (AA 300-647) antibodySMARCC2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 2 (SMARCC2) (Internal Region) antibodySMARCC2 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 2 (SMARCC2) (C-Term) antibodySMARCC2 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 2 (SMARCC2) (Internal Region) antibodySMARCC2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 2 (SMARCC2) (Center) antibodySMARCC2 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SMARCC2 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 2 (SMARCC2))
- 别名
- SMARCC2 (SMARCC2 产品)
- 别名
- MGC80068 antibody, BAF170 antibody, CRACC2 antibody, Rsc8 antibody, 5930405J04Rik antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2 L homeolog antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 antibody, smarcc2.L antibody, SMARCC2 antibody, smarcc2 antibody, Smarcc2 antibody
- 背景
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Background: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Can stimulate the ATPase activity of the catalytic subunit of these complexes. May be required for CoREST dependent repression of neuronal specific gene promoters in non-neuronal cells. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth
Aliases: BAF 170 antibody, BAF170 antibody, BRG1 associated factor 170 antibody, BRG1-associated factor 170 antibody, Chromatin remodeling complex BAF170 subunit antibody, CRACC 2 antibody, CRACC2 antibody, Mammalian chromatin remodeling complex BRG1 associated factor 170 antibody, Rsc 8 antibody, Rsc8 antibody, SMARCC 2 antibody, Smarcc2 antibody, SMRC2_HUMAN antibody, SWI/SNF complex 170 kDa subunit antibody, SWI/SNF complex subunit SMARCC2 antibody, SWI/SNF related matrix associated actin dependent regulator of chromatin c2 antibody, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily c member 2 antibody, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 antibody, SWI3 like protein antibody
- UniProt
- Q8TAQ2
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