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SPOP-B 抗体 (AA 48-374)

SPOP-B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7170432
发货至: 中国
  • 抗原 See all SPOP-B 抗体
    SPOP-B (Speckle-Type POZ Protein (SPOP-B))
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 48-374
    适用
    • 57
    • 18
    • 13
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 56
    • 4
    克隆类型
    • 56
    • 4
    多克隆
    标记
    • 25
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPOP-B antibody is un-conjugated
    应用范围
    • 49
    • 23
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Speckle-type POZ protein (48-374AA)
    亚型
    IgG
    Top Product
    Discover our top product SPOP-B Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SPOP-B (Speckle-Type POZ Protein (SPOP-B))
    别名
    SPOP (SPOP-B 产品)
    别名
    BTBD32 antibody, TEF2 antibody, AI315626 antibody, Pcif1 antibody, zgc:64140 antibody, spop antibody, tef2 antibody, speckle type BTB/POZ protein antibody, speckle-type POZ protein antibody, speckle type POZ protein S homeolog antibody, SPOP antibody, Spop antibody, spop antibody, spop.S antibody
    背景

    Background: Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of H2AFY and BMI1, this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOP has higher ubiquitin ligase activity than the complex that contains the heterodimer formed by SPOP and SPOPL.

    Aliases: BTBD32 antibody, HIB homolog 1 antibody, Roadkill homolog 1 antibody, Speckle type POZ protein antibody, Speckle-type POZ protein antibody, SPOP antibody, SPOP_HUMAN antibody, TEF 2 antibody, TEF2 antibody

    UniProt
    O43791
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