SIGIRR 抗体 (AA 1-120)
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- 抗原 See all SIGIRR 抗体
- SIGIRR (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR))
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抗原表位
- AA 1-120
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIGIRR antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Single Ig IL-1-related receptor protein (1-120AA)
- 亚型
- IgG
- Top Product
- Discover our top product SIGIRR Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SIGIRR (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR))
- 别名
- SIGIRR (SIGIRR 产品)
- 别名
- TIR8 antibody, AI256711 antibody, sc:d148 antibody, RGD1306732 antibody, single Ig and TIR domain containing antibody, single immunoglobulin and toll-interleukin 1 receptor (TIR) domain antibody, SIGIRR antibody, Sigirr antibody, sigirr antibody
- 背景
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Background: Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.
Aliases: Ig IL1 related receptor antibody, MGC110992 antibody, SIGIR_HUMAN antibody, SIGIRR antibody, Single Ig IL 1 related receptor antibody, Single Ig IL-1-related receptor antibody, Single Ig IL-1R-related molecule antibody, Single Ig IL1R Related Molecule antibody, Single immunoglobulin and toll interleukin 1 receptor (TIR) domain antibody, Single immunoglobulin and toll interleukin 1 receptor domain antibody, Single immunoglobulin domain containing IL1R related protein antibody, Single immunoglobulin domain IL1R1 related antibody, Single immunoglobulin domain-containing IL1R-related protein antibody, TIR 8 antibody, TIR8 antibody, Toll/interleukin 1 receptor 8 antibody, Toll/interleukin-1 receptor 8 antibody
- UniProt
- Q6IA17
- 途径
- Toll-Like Receptors Cascades
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