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SIGIRR 抗体 (AA 1-120)

SIGIRR 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7169723
发货至: 中国
  • 抗原 See all SIGIRR 抗体
    SIGIRR (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR))
    抗原表位
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    AA 1-120
    适用
    • 22
    • 13
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 25
    • 4
    • 1
    克隆类型
    • 25
    • 5
    多克隆
    标记
    • 22
    • 6
    • 2
    This SIGIRR antibody is un-conjugated
    应用范围
    • 28
    • 13
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    交叉反应
    人, 小鼠
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Single Ig IL-1-related receptor protein (1-120AA)
    亚型
    IgG
    Top Product
    Discover our top product SIGIRR Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SIGIRR (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR))
    别名
    SIGIRR (SIGIRR 产品)
    别名
    TIR8 antibody, AI256711 antibody, sc:d148 antibody, RGD1306732 antibody, single Ig and TIR domain containing antibody, single immunoglobulin and toll-interleukin 1 receptor (TIR) domain antibody, SIGIRR antibody, Sigirr antibody, sigirr antibody
    背景

    Background: Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.

    Aliases: Ig IL1 related receptor antibody, MGC110992 antibody, SIGIR_HUMAN antibody, SIGIRR antibody, Single Ig IL 1 related receptor antibody, Single Ig IL-1-related receptor antibody, Single Ig IL-1R-related molecule antibody, Single Ig IL1R Related Molecule antibody, Single immunoglobulin and toll interleukin 1 receptor (TIR) domain antibody, Single immunoglobulin and toll interleukin 1 receptor domain antibody, Single immunoglobulin domain containing IL1R related protein antibody, Single immunoglobulin domain IL1R1 related antibody, Single immunoglobulin domain-containing IL1R-related protein antibody, TIR 8 antibody, TIR8 antibody, Toll/interleukin 1 receptor 8 antibody, Toll/interleukin-1 receptor 8 antibody

    UniProt
    Q6IA17
    途径
    Toll-Like Receptors Cascades
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