RUNX2 抗体 (AA 219-404)
Quick Overview for RUNX2 抗体 (AA 219-404) (ABIN7168485)
抗原
See all RUNX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 219-404
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Runt-related transcription factor 2 protein (219-404AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:5000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
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别名
- RUNX2
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背景
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Background: Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5\'-PYGPYGGT-3\', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.
Aliases: Acute myeloid leukemia 3 protein antibody, Alpha subunit 1 antibody, AML3 antibody, CBF alpha 1 antibody, CBF-alpha-1 antibody, CBFA1 antibody, CCD antibody, CCD1 antibody, Cleidocranial dysplasia 1 antibody, Core binding factor antibody, Core binding factor runt domain alpha subunit 1 antibody, Core binding factor subunit alpha 1 antibody, Core-binding factor subunit alpha-1 antibody, MGC120022 antibody, MGC120023 antibody, Oncogene AML 3 antibody, Oncogene AML-3 antibody, OSF 2 antibody, OSF-2 antibody, OSF2 antibody, Osteoblast specific transcription factor 2 antibody, Osteoblast-specific transcription factor 2 antibody, OTTHUMP00000016533 antibody, PEA2 alpha A antibody, PEA2-alpha A antibody, PEA2aA antibody, PEBP2 alpha A antibody, PEBP2-alpha A antibody, PEBP2A1 antibody, PEBP2A2 antibody, PEBP2aA antibody, PEBP2aA1 antibody, Polyomavirus enhancer binding protein 2 alpha A subunit antibody, Polyomavirus enhancer-binding protein 2 alpha A subunit antibody, Runt domain antibody, Runt related transcription factor 2 antibody, Runt-related transcription factor 2 antibody, RUNX2 antibody, RUNX2_HUMAN antibody, SL3 3 enhancer factor 1 alpha A subunit antibody, SL3-3 enhancer factor 1 alpha A subunit antibody, SL3/AKV core binding factor alpha A subunit antibody, SL3/AKV core-binding factor alpha A subunit antibody
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UniProt
- Q13950
抗原
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