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PTPRE 抗体

PTPRE 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7167503
发货至: 中国
  • 抗原 See all PTPRE 抗体
    PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))
    适用
    • 48
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    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
    宿主
    • 44
    • 4
    克隆类型
    • 45
    • 3
    多克隆
    标记
    • 26
    • 4
    • 3
    • 3
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    • 1
    • 1
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    • 1
    This PTPRE antibody is un-conjugated
    应用范围
    • 35
    • 26
    • 20
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    交叉反应
    人, 小鼠
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Receptor-type tyrosine-protein phosphatase epsilon protein
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))
    别名
    PTPRE (PTPRE 产品)
    别名
    ptpra antibody, HPTPE antibody, PTPE antibody, R-PTP-EPSILON antibody, PTPe antibody, PTPepsilon antibody, RPTPepsilon antibody, protein tyrosine phosphatase, receptor type E L homeolog antibody, protein tyrosine phosphatase, receptor type E antibody, protein tyrosine phosphatase, receptor type, E antibody, ptpre.L antibody, PTPRE antibody, Ptpre antibody
    背景

    Background: Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity).Isoform 2 acts as a negative regulator of insulin receptor (IR) signaling in skeletal muscle. Regulates insulin-induced tyrosine phosphorylation of insulin receptor (IR) and insulin receptor substrate 1 (IRS-1), phosphorylation of protein kinase B and glycogen synthase kinase-3 and insulin induced stimulation of glucose uptake.Isoform 1 and isoform 2 act as a negative regulator of FceRI-mediated signal transduction leading to cytokine production and degranulation, most likely by acting at the level of SYK to affect downstream events such as phosphorylation of SLP76 and LAT and mobilization of Ca2+.

    Aliases: DKFZp313F1310 antibody, FLJ57799 antibody, FLJ58245 antibody, HPTPE antibody, Protein tyrosine phosphatase epsilon antibody, Protein tyrosine phosphatase receptor type E antibody, Protein tyrosine phosphatase receptor type epsilon antibody, Protein tyrosine phosphatase receptor type epsilon polypeptide antibody, Protein-tyrosine phosphatase epsilon antibody, PTPE antibody, Ptpre antibody, PTPRE_HUMAN antibody, R PTP Epsilon antibody, R-PTP-epsilon antibody, Receptor-type tyrosine-protein phosphatase epsilon antibody

    UniProt
    P23469
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