HBEGF 抗体 (AA 63-148)
Quick Overview for HBEGF 抗体 (AA 63-148) (ABIN7164700)
抗原
See all HBEGF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 63-148
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Proheparin-binding EGF-like growth factor protein (63-148AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
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别名
- HBEGF
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背景
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Background: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
Aliases: diphtheria toxin receptor (heparin-binding EGF-like growth factor) antibody, diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor) antibody, Diphtheria toxin receptor antibody, DT R antibody, DT-R antibody, DTR antibody, DTS antibody, DTSF antibody, HB-EGF antibody, HBEGF antibody, HBEGF_HUMAN antibody, HEGFL antibody, Heparin binding EGF like growth factor antibody, Heparin binding epidermal growth factor antibody, Heparin binding epidermal growth factor like growth factor antibody, Heparin-binding EGF-like growth factor antibody, Proheparin binding EGF like growth factor antibody
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UniProt
- Q99075
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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