Tuberin 抗体 (pSer664) (HRP)
Quick Overview for Tuberin 抗体 (pSer664) (HRP) (ABIN712145)
抗原
See all Tuberin (TSC2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer664
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human Tuberin around the phosphorylation site of Ser664
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亚型
- IgG
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应用备注
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WB: 1:100-1000, IHC-P: 1:100-500
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % Gentamicin.
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储存液
- Gentamicin sulfate
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注意事项
- This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at 4 °C
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有效期
- 12 months
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- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
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别名
- Tsc2
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背景
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Tuberin, or TSC2 (Tuberous sclerosis complex), is implicated as a tumor suppressor. It may function in vesicular transport, and may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between hamartin (TSC1) and tuberin may facilitate vesicular docking. It specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth. Mutations in tuberin lead to constitutive activation of RAP1A in tumors. At least three isoforms of Tuberin exist.
Synonyms: TSC2phospho S664,FLJ43106, LAM, TSC2, TSC2_HUMAN, TSC4, Tuberin, Tuberous sclerosis 2 protein. -
基因ID
- 7249
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途径
- RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
抗原
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