-
- 抗原 See all PHAX 抗体
- PHAX (phosphorylated Adaptor For RNA Export (PHAX))
-
抗原表位
- AA 6-243
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PHAX antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Phosphorylated adapter RNA export protein (6-243AA)
- 亚型
- IgG
-
anti-phosphorylated Adaptor For RNA Export (PHAX) (AA 297-326), (C-Term) antibody
PHAX 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32550 unconjugated
anti-phosphorylated Adaptor For RNA Export (PHAX) (AA 304-334), (C-Term) antibodyPHAX 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- PHAX (phosphorylated Adaptor For RNA Export (PHAX))
- 别名
- PHAX (PHAX 产品)
- 别名
- RNUXA antibody, 2810055C14Rik antibody, 4933427L19Rik antibody, AU018701 antibody, AU018854 antibody, D18Ertd65e antibody, Rnuxa antibody, p55 antibody, phosphorylated adaptor for RNA export antibody, PHAX antibody, Phax antibody
- 背景
-
Background: A phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. Bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other. Its phosphorylation in the nucleus is required for U snRNA export complex assembly and export, while its dephosphorylation in the cytoplasm causes export complex disassembly. It is recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Its compartmentalized phosphorylation cycle may also contribute to the directionality of export. Binds strongly to m7G-capped U1 and U5 small nuclear RNAs (snRNAs) in a sequence-unspecific manner and phosphorylation-independent manner (By similarity). Plays also a role in the biogenesis of U3 small nucleolar RNA (snoRNA). Involved in the U3 snoRNA transport from nucleoplasm to Cajal bodies. Binds strongly to m7G-capped U3, U8 and U13 precursor snoRNAs and weakly to trimethylated (TMG)-capped U3, U8 and U13 snoRNAs. Binds also to telomerase RNA.
Aliases: FLJ13193 antibody, PHAX antibody, PHAX_HUMAN antibody, Phosphorylated adapter RNA export protein antibody, Phosphorylated adaptor for RNA export antibody, RNA U small nuclear RNA export adapter protein antibody, RNA U, small nuclear RNA export adapter (phosphorylation regulated) antibody, RNUXA antibody
- UniProt
- Q9H814
- 途径
- Ribonucleoprotein Complex Subunit Organization
-
You are here:
