PIK3R2 抗体 (Regulatory Subunit beta)
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- 抗原 See all PIK3R2 (PI3K p85b) 抗体
- PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))
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抗原表位
- AA 75-125, Regulatory Subunit beta
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIK3R2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Phosphatidylinositol 3-kinase regulatory subunit beta protein (75-125AA)
- 亚型
- IgG
- Top Product
- Discover our top product PI3K p85b Primary Antibody
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anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibody
PI3K p85b 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 1-60) antibodyPI3K p85b 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠, Cow, 犬 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (Thr232) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (Tyr464) antibodyPI3K p85b 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 430-470) antibodyPI3K p85b 适用: 人 WB 宿主: 兔 Polyclonal RB48985 unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (Tyr467) antibodyPI3K p85b 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 447-461), (Middle Region) antibodyPI3K p85b 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 268-298), (C-Term) antibodyPI3K p85b 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1716 unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))
- 别名
- PIK3R2 (PI3K p85b 产品)
- 别名
- MPPH antibody, P85B antibody, p85 antibody, p85-BETA antibody, pik3r2 antibody, MGC80449 antibody, p85beta antibody, phosphoinositide-3-kinase regulatory subunit 2 antibody, phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta) antibody, phosphoinositide-3-kinase, regulatory subunit 2 (beta) antibody, PIK3R2 antibody, pik3r2 antibody, Pik3r2 antibody
- 背景
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Background: Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Indirectly regulates autophagy (PubMed:23604317). Promotes nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (By similarity).
Aliases: p85 antibody, p85 beta antibody, P85B antibody, P85B_HUMAN antibody, Phosphatidylinositol 3 kinase antibody, Phosphatidylinositol 3 kinase regulatory beta subunit antibody, Phosphatidylinositol 3 kinase regulatory subunit beta antibody, Phosphatidylinositol 3 kinase regulatory subunit polypeptide 2 antibody, Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 2 (p85 beta) antibody, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta antibody, Phosphatidylinositol 3-kinase regulatory subunit beta antibody, Phosphoinositide 3 kinase regulatory subunit 2 (beta) antibody, Phosphoinositide 3 kinase regulatory subunit 2 antibody, Phosphoinositide 3 kinase regulatory subunit polypeptide 2 (p85 beta) antibody, Phosphoinositide 3 kinase regulatory subunit polypeptide 2 antibody, Phosphoinositide 3 kinase, regulatory subunit 2 (beta) antibody, Phosphoinositide 3 kinase, regulatory subunit 2 (p85 beta) antibody, PI3 kinase p85 beta subunit antibody, PI3 kinase p85 subunit beta antibody, PI3-kinase regulatory subunit beta antibody, PI3-kinase subunit p85-beta antibody, PI3K antibody, PI3K regulatory subunit beta antibody, PIK3R 2 antibody, PIK3R2 antibody, PtdIns 3 kinase p85 beta antibody, PtdIns-3-kinase regulatory subunit beta antibody, PtdIns-3-kinase regulatory subunit p85-beta antibody
- UniProt
- O00459
- 途径
- VEGF Signaling, BCR Signaling
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