ABCB4 抗体 (AA 530-693) (HRP)
-
- 抗原 See all ABCB4 抗体
- ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))
-
抗原表位
- AA 530-693
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ABCB4 antibody is conjugated to HRP
-
应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Phosphatidylcholine translocator ABCB4 protein (530-693AA)
- 亚型
- IgG
- Top Product
- Discover our top product ABCB4 Primary Antibody
-
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) (AA 601-720) antibody
ABCB4 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) (AA 624-654) antibodyABCB4 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB02209 unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) (AA 601-720) antibodyABCB4 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) (AA 1034-1276) antibodyABCB4 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) (AA 530-693) antibodyABCB4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) (AA 252-301) antibodyABCB4 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) (AA 1-110) antibodyABCB4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) (AA 624-654) antibodyABCB4 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) antibodyABCB4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) (N-Term) antibodyABCB4 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 绵羊, Pig WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))
- 别名
- ABCB4 (ABCB4 产品)
- 别名
- ABC21 antibody, GBD1 antibody, ICP3 antibody, MDR2 antibody, MDR2/3 antibody, MDR3 antibody, PFIC-3 antibody, PGY3 antibody, zgc:172149 antibody, Mdr2 antibody, Pgy-2 antibody, Pgy2 antibody, mdr-2 antibody, Pgy3 antibody, ABCB4a antibody, DEFB1 antibody, PGP2 antibody, PGY2 antibody, PGP3 antibody, ABCB4 antibody, RUNDC3B antibody, ATP binding cassette subfamily B member 4 antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 4 antibody, beta-defensin 1-like antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 1B antibody, RUN domain-containing protein 3B antibody, ABCB4 antibody, abcb4 antibody, Abcb4 antibody, LOC100861170 antibody, Abcb1b antibody, LOC101122517 antibody
- 背景
-
Background: Energy-dependent phospholipid efflux translocator that acts as a positive regulator of biliary lipid secretion. Functions as a floppase that translocates specifically phosphatidylcholine (PC) from the inner to the outer leaflet of the canalicular membrane bilayer into the canaliculi of hepatocytes. Translocation of PC makes the biliary phospholipids available for extraction into the canaliculi lumen by bile salt mixed micelles and therefore protects the biliary tree from the detergent activity of bile salts (PubMed:7957936, PubMed:8898203, PubMed:9366571, PubMed:17523162, PubMed:23468132, PubMed:24806754, PubMed:24723470, PubMed:24594635, PubMed:21820390). Plays a role in the recruitment of phosphatidylcholine (PC), phosphatidylethanolamine (PE) and sphingomyelin (SM) molecules to nonraft membranes and to fu rther enrichment of SM and cholesterol in raft membranes in hepatocytes (PubMed:23468132). Required for proper phospholipid bile formation (By similarity). Indirectly involved in cholesterol efflux activity from hepatocytes into the canalicular lumen in the presence of bile salts in an ATP-dependent manner (PubMed:24045840). May promote biliary phospholipid secretion as canaliculi-containing vesicles from the canalicular plasma membrane (PubMed:9366571). In cooperation with ATP8B1, functions to protect hepatocytes from the deleterious detergent activity of bile salts (PubMed:21820390). Does not confer multidrug resistance (By similarity).
Aliases: ABC 21 antibody, ABC B4 antibody, ABC21 antibody, ABCB 4 antibody, Abcb4 antibody, ABCB4 protein antibody, ATP binding cassette sub family B MDR/TAP member 4 antibody, ATP binding cassette sub family B member 4 antibody, ATP-binding cassette sub-family B member 4 antibody, GBD1 antibody, ICP3 antibody, MDR 3 antibody, MDR2 antibody, MDR2/3 antibody, MDR3 antibody, MDR3 P glycoprotein antibody, MDR3 P gp antibody, MDR3_HUMAN antibody, Multidrug resistance protein 3 antibody, Multiple drug resistance 3 antibody, P glycoprotein 3 antibody, P-glycoprotein 3 antibody, PFIC 3 antibody, PFIC3 antibody, PGY 3 antibody, PGY3 antibody
- UniProt
- P21439
- 途径
- Regulation of Lipid Metabolism by PPARalpha
-
