ZC3HC1 抗体 (AA 1-260)
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- 抗原 See all ZC3HC1 抗体
- ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))
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抗原表位
- AA 1-260
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZC3HC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Nuclear-interacting partner of ALK protein (1-260AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))
- 别名
- ZC3HC1 (ZC3HC1 产品)
- 别名
- 1110054L24Rik antibody, AU018540 antibody, AU019789 antibody, HSPC216 antibody, Nipa antibody, NIPA antibody, RGD1561099 antibody, zinc finger, C3HC type 1 antibody, zinc finger C3HC-type containing 1 antibody, zinc finger, C3HC-type containing 1 antibody, Zc3hc1 antibody, ZC3HC1 antibody
- 背景
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Background: Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.
Aliases: hNIPA antibody, NIPA_HUMAN antibody, Nuclear interacting partner of ALK antibody, Nuclear interacting partner of anaplastic lymphoma kinase antibody, Nuclear-interacting partner of ALK antibody, Nuclear-interacting partner of anaplastic lymphoma kinase antibody, zc3hc1 antibody, Zinc finger C3HC type containing 1 antibody, Zinc finger C3HC-type protein 1 antibody
- UniProt
- Q86WB0
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