NFATC1 抗体 (AA 48-406)
Quick Overview for NFATC1 抗体 (AA 48-406) (ABIN7161789)
抗原
See all NFATC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 48-406
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Nuclear factor of activated T-cells, cytoplasmic 1 protein (48-406AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:1000-1:2000, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
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别名
- NFATC1
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背景
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Background: Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells (PubMed:10358178). Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function (By similarity).
Aliases: cytoplasmic 1 antibody, MGC138448 antibody, NF ATc antibody, NF ATc1 antibody, NF-ATc antibody, NF-ATc1 antibody, NF-ATc1.2 antibody, NFAC1_HUMAN antibody, NFAT 2 antibody, NFAT transcription complex cytosolic component antibody, NFATC 1 antibody, NFATc antibody, NFATc1 antibody, Nuclear factor of activated T cells cytoplasmic 1 antibody, Nuclear factor of activated T cells cytoplasmic calcineurin dependent 1 antibody, Nuclear factor of activated T cells cytosolic component 1 antibody, nuclear factor of activated T-cells 'c' antibody, Nuclear factor of activated T-cells antibody
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UniProt
- O95644
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途径
- RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway
抗原
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