GPR18 抗体 (AA 290-331) (HRP)
Quick Overview for GPR18 抗体 (AA 290-331) (HRP) (ABIN7160752)
抗原
See all GPR18 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 290-331
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human N-arachidonyl glycine receptor protein (290-331AA)
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亚型
- IgG
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anti-G Protein-Coupled Receptor 18 (GPR18) (AA 290-331) antibody
GPR18 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 18 (GPR18) (AA 1-50) antibodyGPR18 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 18 (GPR18) (Extracellular Domain) antibodyGPR18 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 18 (GPR18) (Cytoplasmic Domain) antibodyGPR18 适用: 人, 猴, Bat, 马, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 18 (GPR18) (Cytoplasmic Domain) antibodyGPR18 适用: 人 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 18 (GPR18) (AA 114-168) antibodyGPR18 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 18 (GPR18) (Extracellular Domain) antibodyGPR18 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 18 (GPR18) (AA 144-193) antibodyGPR18 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 18 (GPR18) (Internal Region) antibodyGPR18 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 18 (GPR18) (AA 191-240) antibodyGPR18 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GPR18 (G Protein-Coupled Receptor 18 (GPR18))
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别名
- GPR18
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背景
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Background: Receptor for endocannabinoid N-arachidonyl glycine (NAGly) (PubMed:16844083, PubMed:24762058, PubMed:27572937). However, conflicting results about the role of NAGly as an agonist are reported (PubMed:27018161). Can also be activated by plant-derived and synthetic cannabinoid agonists (PubMed:24762058). The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase (PubMed:16844083). May contribute to regulation of the immune system. Is required for normal homeostasis of CD8+ subsets of intraepithelial lymphocytes (IELs) (CD8alphaalpha and CD8alphabeta IELs)in small intstine by supporting preferential migration of CD8alphaalpha T-cells to intraepithelial compartment over lamina propria compartment, and by mediating their reconstitution into small intestine after bone marrow transplant (By similarity). Plays a role in hypotensive responses, mediating reduction in intraocular and blood pressure (By similarity). Mediates NAGly-induced process of reorganization of actin filaments and induction of acrosomal exocytosis (PubMed:27572937).
Aliases: GPR18 antibody, GPCRWN-arachidonyl glycine receptor antibody, NAGly receptor antibody, G-protein coupled receptor 18 antibody
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UniProt
- Q14330
抗原
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