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GPR18 抗体 (AA 290-331)

GPR18 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7160749
发货至: 中国
  • 抗原 See all GPR18 抗体
    GPR18 (G Protein-Coupled Receptor 18 (GPR18))
    抗原表位
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    AA 290-331
    适用
    • 32
    • 12
    • 9
    • 6
    • 2
    • 2
    • 2
    • 1
    宿主
    • 33
    克隆类型
    • 33
    多克隆
    标记
    • 26
    • 3
    • 2
    • 2
    This GPR18 antibody is un-conjugated
    应用范围
    • 15
    • 14
    • 11
    • 9
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human N-arachidonyl glycine receptor protein (290-331AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    GPR18 (G Protein-Coupled Receptor 18 (GPR18))
    别名
    GPR18 (GPR18 产品)
    别名
    GPR18 antibody, G protein-coupled receptor 18 antibody, GPR18 antibody, Gpr18 antibody
    背景

    Background: Receptor for endocannabinoid N-arachidonyl glycine (NAGly) (PubMed:16844083, PubMed:24762058, PubMed:27572937). However, conflicting results about the role of NAGly as an agonist are reported (PubMed:27018161). Can also be activated by plant-derived and synthetic cannabinoid agonists (PubMed:24762058). The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase (PubMed:16844083). May contribute to regulation of the immune system. Is required for normal homeostasis of CD8+ subsets of intraepithelial lymphocytes (IELs) (CD8alphaalpha and CD8alphabeta IELs)in small intstine by supporting preferential migration of CD8alphaalpha T-cells to intraepithelial compartment over lamina propria compartment, and by mediating their reconstitution into small intestine after bone marrow transplant (By similarity). Plays a role in hypotensive responses, mediating reduction in intraocular and blood pressure (By similarity). Mediates NAGly-induced process of reorganization of actin filaments and induction of acrosomal exocytosis (PubMed:27572937).

    Aliases: GPR18 antibody, GPCRWN-arachidonyl glycine receptor antibody, NAGly receptor antibody, G-protein coupled receptor 18 antibody

    UniProt
    Q14330
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