GPR18 抗体 (Internal Region)
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- 抗原 See all GPR18 抗体
- GPR18 (G Protein-Coupled Receptor 18 (GPR18))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GPR18 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- GPR18 Antibody detects endogenous levels of total GPR18.
- 预测反应
- Horse,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human GPR18, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product GPR18 Primary Antibody
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anti-G Protein-Coupled Receptor 18 (GPR18) (AA 290-331) antibody
GPR18 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 18 (GPR18) (Extracellular Domain) antibodyGPR18 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 18 (GPR18) (Cytoplasmic Domain) antibodyGPR18 适用: 人 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 18 (GPR18) (Cytoplasmic Domain) antibodyGPR18 适用: 人, 猴, 兔, 马, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 18 (GPR18) (AA 1-50) antibodyGPR18 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 18 (GPR18) (AA 114-168) antibodyGPR18 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 18 (GPR18) (Extracellular Domain) antibodyGPR18 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 18 (GPR18) (AA 144-193) antibodyGPR18 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 18 (GPR18) antibodyGPR18 适用: 人, 小鼠, 猴, Gorilla, 兔, 马 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 18 (GPR18) (1st Extracellular Domain) antibodyGPR18 适用: 人, Gorilla IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- GPR18 (G Protein-Coupled Receptor 18 (GPR18))
- 别名
- GPR18 (GPR18 产品)
- 别名
- GPR18 antibody, G protein-coupled receptor 18 antibody, GPR18 antibody, Gpr18 antibody
- 背景
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Description: Receptor for endocannabinoid N-arachidonyl glycine (NAGly) (PubMed:16844083, PubMed:24762058, PubMed:27572937). However, conflicting results about the role of NAGly as an agonist are reported (PubMed:27018161). Can also be activated by plant-derived and synthetic cannabinoid agonists (PubMed:24762058). The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase (PubMed:16844083). May contribute to regulation of the immune system. Is required for normal homeostasis of CD8+ subsets of intraepithelial lymphocytes (IELs) (CD8alphaalpha and CD8alphabeta IELs)in small intstine by supporting preferential migration of CD8alphaalpha T-cells to intraepithelial compartment over lamina propria compartment, and by mediating their reconstitution into small intestine after bone marrow transplant (By similarity). Plays a role in hypotensive responses, mediating reduction in intraocular and blood pressure (By similarity). Mediates NAGly-induced process of reorganization of actin filaments and induction of acrosomal exocytosis (PubMed:27572937).
Gene: GPR18
- 分子量
- 35 kDa
- 基因ID
- 2841
- UniProt
- Q14330
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