MAPK10 抗体 (AA 133-316) (HRP)
Quick Overview for MAPK10 抗体 (AA 133-316) (HRP) (ABIN7159979)
抗原
See all MAPK10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 133-316
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原理
- MAPK10 Antibody, HRP conjugated
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human Mitogen-activated protein kinase 10 protein (133-316AA)
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 175-464) antibody
MAPK10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 180-329) antibodyMAPK10 适用: 人, 大鼠 WB, ELISA 宿主: 小鼠 Monoclonal 2B10H12 unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 88-332) antibodyMAPK10 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 133-316) antibodyMAPK10 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 28-233) antibodyMAPK10 适用: 人, 小鼠 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 10E4A4 unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (C-Term) antibodyMAPK10 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (C-Term) antibodyMAPK10 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (AA 1-319) antibodyMAPK10 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E12-1F7 unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) (C-Term) antibodyMAPK10 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 10 (MAPK10) antibodyMAPK10 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 8A5D11 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
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别名
- MAPK10
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背景
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Background: Serine/threonine-protein kinase involved in various processes such as neuronal proliferation, differentiation, migration and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK10/JNK3. In turn, MAPK10/JNK3 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity. Plays regulatory roles in the signaling pathways during neuronal apoptosis. Phosphorylates the neuronal microtubule regulator STMN2. Acts in the regulation of the beta-amyloid precursor protein/APP signaling during neuronal differentiation by phosphorylating APP. Participates also in neurite growth in spiral ganglion neurons. Phosphorylates the CLOCK-ARNTL/BMAL1 heterodimer and plays a role in the photic regulation of the circadian clock (PubMed:22441692).
Aliases: c Jun kinase 3 antibody, c-Jun N-terminal kinase 3 antibody, cJun N terminal kinase 3 antibody, FLJ12099 antibody, FLJ33785 antibody, JNK3 alpha protein kinase antibody, JNK3 antibody, JNK3A antibody, MAP kinase 10 antibody, MAP kinase antibody, MAP kinase p49 3F12 antibody, MAPK 10 antibody, Mapk10 antibody, MGC50974 antibody, mitogen activated protein kinase 10 antibody, Mitogen-activated protein kinase 10 antibody, MK10_HUMAN antibody, p493F12 antibody, p54bSAPK antibody, PRKM10 antibody, protein kinase mitogen activated 10 antibody, SAPK1b antibody, Stress activated protein kinase 1b antibody, stress activated protein kinase beta antibody, Stress activated protein kinase JNK3 antibody, Stress-activated protein kinase JNK3 antibody
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UniProt
- P53779
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途径
- MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
抗原
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