MGMT 抗体 (AA 4-207)
Quick Overview for MGMT 抗体 (AA 4-207) (ABIN7159622)
抗原
See all MGMT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-207
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Methylated-DNA--protein-cysteine methyltransferase protein (4-207AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:10-1:100,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
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别名
- MGMT
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背景
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Background: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Aliases: 6 O methylguanine DNA methyltransferase antibody, 6-O-methylguanine-DNA methyltransferase antibody, Agat antibody, AGT antibody, AI267024 antibody, EC 2.1.1.63 antibody, Methylated DNA protein cysteine methyltransferase antibody, Methylated-DNA--protein-cysteine methyltransferase antibody, Methylguanine DNA methyltransferase antibody, MGC107020 antibody, MGMT antibody, MGMT_HUMAN antibody, O 6 methylguanine DNA alkyltransferase antibody, O 6 methylguanine DNA methyltransferase antibody, O-6-methylguanine-DNA methyltransferase antibody, O-6-methylguanine-DNA-alkyltransferase antibody
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UniProt
- P16455
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途径
- DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
抗原
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