INSIG1 抗体 (AA 1-87)
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北京 101111
Quick Overview for INSIG1 抗体 (AA 1-87) (ABIN7156348)
抗原
See all INSIG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-87
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原理
- INSIG1 Antibody
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human Insulin-induced gene 1 protein (1-87AA)
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亚型
- IgG
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anti-Insulin Induced Gene 1 (INSIG1) (Internal Region) antibody
INSIG1 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 63-112) antibodyINSIG1 适用: 人, 小鼠, 大鼠, Cow, 山羊, 马, 兔, 犬, 豚鼠, Pig, 猴, Hamster, 非洲爪蟾, Bat, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 36-63), (N-Term) antibodyINSIG1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21689 unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibodyINSIG1 适用: 人, 小鼠, 大鼠, Cow, 山羊, 马, 兔, 犬, 豚鼠, 绵羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 71-120) antibodyINSIG1 适用: 人, 小鼠, 大鼠, Cow, 山羊, 马, 兔, 绵羊, Pig, Hamster, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (C-Term) antibodyINSIG1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibodyINSIG1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibodyINSIG1 适用: 人, 小鼠, 大鼠, Cow, 山羊, 马, 兔, 犬, 豚鼠, 绵羊, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- INSIG1 (Insulin Induced Gene 1 (INSIG1))
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别名
- INSIG1
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背景
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Background: Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Initiates the sterol-mediated ubiquitin-mediated endoplasmic reticulum-associated degradation (ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligase, AMFR/gp78. May play a role in growth and differentiation of tissues involved in metabolic control. May play a regulatory role during G0/G1 transition of cell growth.
Aliases: CL 6 antibody, CL6 antibody, INSI1_HUMAN antibody, INSIG 1 antibody, INSIG 1 membrane protein antibody, INSIG-1 antibody, insig1 antibody, INSIG1 membrane protein antibody, Insulin induced gene 1 antibody, Insulin induced gene 1 protein antibody, Insulin-induced gene 1 protein antibody, MGC1405 antibody
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UniProt
- O15503
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途径
- ER-Nucleus Signaling
抗原
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