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- 抗原 See all IGHA2 products
- IGHA2 (Immunoglobulin Heavy Constant alpha 2 (A2m Marker) (IGHA2))
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抗原表位
- AA 36-111
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IGHA2 antibody is un-conjugated
- 应用范围
- ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Immunoglobulin heavy constant alpha 2 protein (36-111AA)
- 亚型
- IgG
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anti-Immunoglobulin Heavy Constant alpha 2 (A2m Marker) (IGHA2) (AA 1-477) antibody
IGHA2 适用: 人 IF, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant alpha 2 (A2m Marker) (IGHA2) (AA 1-477) antibodyIGHA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- IGHA2 (Immunoglobulin Heavy Constant alpha 2 (A2m Marker) (IGHA2))
- 别名
- IGHA2 (IGHA2 产品)
- 别名
- immunoglobulin heavy constant alpha 2 (A2m marker) antibody, IGHA2 antibody
- 背景
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Background: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). Ig alpha is the major immunoglobulin class in body secretions (PubMed:2241915).
Aliases: IGHA2Immunoglobulin heavy constant alpha 2 antibody, Ig alpha-2 chain C region antibody, Ig alpha-2 chain C region BUT antibody, Ig alpha-2 chain C region LAN antibody
- UniProt
- P01877
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