Vpx Protein (VPX) (AA 1-113), (subtype A) 抗体 (Biotin)
-
- 抗原 See all Vpx Protein (VPX) 抗体
- Vpx Protein (VPX)
-
抗原表位
- AA 1-113, subtype A
-
适用
- Human Immunodeficiency Virus (HIV)
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- Biotin
-
应用范围
- ELISA
- 交叉反应
- Human Immunodeficiency Virus (HIV)
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human immunodeficiency virus type 2 subtype A Protein Vpx protein (1-113AA)
- 亚型
- IgG
- Top Product
- Discover our top product VPX Primary Antibody
-
anti-Vpx Protein (VPX) (AA 1-112), (subtype A) antibody
VPX 适用: Human Immunodeficiency Virus (HIV) ELISA, WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- Vpx Protein (VPX)
- 别名
- vpx (VPX 产品)
- 别名
- vpx protein antibody, vpx antibody
- 物质类
- Viral Protein
- 背景
-
Background: Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription.
Aliases: vpxProtein Vpx antibody, Viral protein X antibody, X ORF protein antibody
- UniProt
- P18099
-
