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- 抗原 See all MLL5/KMT2E (MLL5) 抗体
- MLL5/KMT2E (MLL5) (Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog) (MLL5))
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抗原表位
- AA 182-316
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MLL5/KMT2E antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 小鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Histone-lysine N-methyltransferase 2E protein (182-316AA)
- 亚型
- IgG
- Top Product
- Discover our top product MLL5 Primary Antibody
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anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog) (MLL5) (AA 200-500) antibody
MLL5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog) (MLL5) antibodyMLL5 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog) (MLL5) (AA 1-609) antibodyMLL5 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog) (MLL5) (AA 1-609) antibodyMLL5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog) (MLL5) antibodyMLL5 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog) (MLL5) (AA 93-120), (N-Term) antibodyMLL5 适用: 人 WB 宿主: 兔 Polyclonal RB19215 unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog) (MLL5) (AA 93-120) antibodyMLL5 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- MLL5/KMT2E (MLL5) (Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog) (MLL5))
- 别名
- KMT2E (MLL5 产品)
- 别名
- HDCMC04P antibody, MLL5 antibody, 1810033J14Rik antibody, 9530077A04Rik antibody, D230038D11Rik antibody, Mll5 antibody, lysine methyltransferase 2E antibody, lysine (K)-specific methyltransferase 2E antibody, KMT2E antibody, Kmt2e antibody
- 背景
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Background: Histone methyltransferase that specifically mono- and dimethylates \'Lys-4\' of histone H3 (H3K4me1 and H3K4me2). H3 \'Lys-4\' methylation represents a specific tag for epigenetic transcriptional activation. Key regulator of hematopoiesis involved in terminal myeloid differentiation and in the regulation of hematopoietic stem cell (HSCs) self-renewal by a mechanism that involves DNA methylation. Plays an essential role in retinoic-acid-induced granulopoiesis by acting as a coactivator of RAR-alpha (RARA) in target gene promoters. Also acts as an important cell cycle regulator, participating in cell cycle regulatory network machinery at multiple cell cycle stages. Required to suppress inappropriate expression of S-phase-promoting genes and maintain expression of determination genes in quiescent cells. Overexpression inhibits cell cycle progression, while knockdown induces cell cycle arrest at both the G1 and G2/M phases.
Aliases: HDCMC04P antibody, Histone lysine N methyltransferase MLL5 antibody, Histone-lysine N-methyltransferase MLL5 antibody, KMT2E antibody, Lysine N methyltransferase 2E antibody, Lysine N-methyltransferase 2E antibody, MGC70452 antibody, Mll5 antibody, MLL5_HUMAN antibody, Myeloid/lymphoid or mixed lineage leukemia 5 (trithorax homolog, Drosophila) antibody, Myeloid/lymphoid or mixed lineage leukemia 5 antibody, Myeloid/lymphoid or mixed lineage leukemia protein 5 antibody, Myeloid/lymphoid or mixed-lineage leukemia protein 5 antibody
- UniProt
- Q8IZD2
- 途径
- Retinoic Acid Receptor Signaling Pathway, Warburg Effect
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