Exonuclease 1 抗体 (AA 301-600) (Biotin)
Quick Overview for Exonuclease 1 抗体 (AA 301-600) (Biotin) (ABIN7152266)
抗原
See all Exonuclease 1 (EXO1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 301-600
-
交叉反应
- 人
-
纯化方法
- >95%, Protein G purified
-
免疫原
- Recombinant Human Exonuclease 1 protein (301-600AA)
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- Exonuclease 1 (EXO1)
-
别名
- EXO1
-
背景
-
Background: 5\'->3\' double-stranded DNA exonuclease which may also possess a cryptic 3\'->5\' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5\' or 3\' to the mismatch. Also exhibits endonuclease activity against 5\'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5\'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.
Aliases: exo1 antibody, EXO1_HUMAN antibody, ExoI antibody, Exonuclease 1 antibody, Exonuclease I antibody, Exonuclease1 antibody, HEX1 antibody, hExo I antibody, hExo1 antibody, hExoI antibody, Rad2 nuclease family member homolog of S. cerevisiae exonuclease 1 antibody
-
UniProt
- Q9UQ84
-
途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
-