POLR3F 抗体 (AA 1-270) (Biotin)
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- 抗原 See all POLR3F 抗体
- POLR3F (Polymerase (RNA) III (DNA Directed) Polypeptide F, 39 KDa (POLR3F))
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抗原表位
- AA 1-270
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POLR3F antibody is conjugated to Biotin
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human DNA-directed RNA polymerase III subunit RPC6 protein (1-270AA)
- 亚型
- IgG
- Top Product
- Discover our top product POLR3F Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- POLR3F (Polymerase (RNA) III (DNA Directed) Polypeptide F, 39 KDa (POLR3F))
- 别名
- POLR3F (POLR3F 产品)
- 别名
- 2810411G20Rik antibody, 3010019O03Rik antibody, 3110032A07Rik antibody, RPC39 antibody, RPC6 antibody, zgc:56299 antibody, zgc:76983 antibody, RNA polymerase III subunit F antibody, polymerase (RNA) III (DNA directed) polypeptide F antibody, POLR3F antibody, Polr3f antibody, polr3f antibody
- 背景
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Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.
Aliases: DNA directed RNA polymerase III 39 kDa polypeptide antibody, DNA directed RNA polymerase III 39 kDa polypeptide F antibody, DNA directed RNA polymerase III subunit F antibody, DNA directed RNA polymerase III subunit RPC6 antibody, DNA directed RNA polymerases III 39 kDa polypeptide antibody, DNA-directed RNA polymerase III subunit F antibody, DNA-directed RNA polymerase III subunit RPC6 antibody, MGC13517 antibody, Polr3f antibody, Polymerase (RNA) III (DNA directed) polypeptide F antibody, RNA polymerase III 39 kDa subunit antibody, RNA polymerase III C39 subunit antibody, RNA polymerase III subunit C6 antibody, RPC 39 antibody, RPC 6 antibody, RPC39 antibody, RPC6 antibody, RPC6_HUMAN antibody
- UniProt
- Q9H1D9
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