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APOBEC3F 抗体 (AA 139-287) (HRP)

APOBEC3F 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7150159
发货至: 中国
  • 抗原 See all APOBEC3F 抗体
    APOBEC3F (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3F (APOBEC3F))
    抗原表位
    • 14
    • 10
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 139-287
    适用
    • 29
    • 2
    • 2
    • 1
    • 1
    宿主
    • 28
    • 1
    克隆类型
    • 29
    多克隆
    标记
    • 16
    • 4
    • 3
    • 2
    • 2
    • 2
    This APOBEC3F antibody is conjugated to HRP
    应用范围
    • 25
    • 17
    • 16
    • 14
    • 5
    • 3
    • 2
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human DNA dC->dU-editing enzyme APOBEC-3F protein (139-287AA)
    亚型
    IgG
    Top Product
    Discover our top product APOBEC3F Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    APOBEC3F (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3F (APOBEC3F))
    别名
    APOBEC3F (APOBEC3F 产品)
    别名
    A3F antibody, ARP8 antibody, BK150C2.4.MRNA antibody, KA6 antibody, APOBEC3F antibody, apolipoprotein B mRNA editing enzyme catalytic subunit 3F antibody, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F antibody, APOBEC3F antibody
    背景

    Background: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA. Exhibits antiviral activity also against hepatitis B virus (HBV), equine infectious anemia virus (EIAV), xenotropic MuLV-related virus (XMRV) and simian foamy virus (SFV) and may inhibit the mobility of LTR and non-LTR retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.

    Aliases: A3F antibody, ABC3F_HUMAN antibody, APOBEC3F antibody, Apolipoprotein B mRNA editing enzyme, catalytic polypeptide like 3F antibody, Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F antibody, ARP8 antibody, DNA dC->dU-editing enzyme APOBEC-3F antibody, Induced upon T cell activation antibody, KA6 antibody

    UniProt
    Q8IUX4
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