APOBEC3D 抗体 (AA 250-371)
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- 抗原 See all APOBEC3D 抗体
- APOBEC3D (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3D (APOBEC3D))
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抗原表位
- AA 250-371
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This APOBEC3D antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human DNA dC->dU-editing enzyme APOBEC-3D protein (250-371AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- APOBEC3D (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3D (APOBEC3D))
- 别名
- APOBEC3D (APOBEC3D 产品)
- 别名
- A3D antibody, APOBEC3DE antibody, APOBEC3E antibody, ARP6 antibody, APOBEC3D antibody, apolipoprotein B mRNA editing enzyme catalytic subunit 3D antibody, APOBEC3D antibody
- 背景
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Background: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. May inhibit the mobility of LTR and non-LTR retrotransposons.
Aliases: A3D antibody, ABC3D_HUMAN antibody, APOBEC3D antibody, APOBEC3DE antibody, APOBEC3E antibody, Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3D antibody, Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3E pseudogene antibody, ARP6 antibody, bK150C2.9 antibody, BK150C2.9 protein antibody, DNA dC >dU editing enzyme APOBEC 3D antibody, DNA dC->dU-editing enzyme APOBEC-3D antibody, hCG_41704 antibody, HCG41704, isoform CRA_b antibody, Probable DNA dC->dU-editing enzyme APOBEC-3D antibody
- UniProt
- Q96AK3
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