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Cytosolic Arginine Sensor For mTORC1 Subunit 2 (CASTOR2) (AA 82-329) 抗体 (HRP)

CASTOR2 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7149382
发货至: 中国
  • 抗原
    Cytosolic Arginine Sensor For mTORC1 Subunit 2 (CASTOR2)
    抗原表位
    AA 82-329
    适用
    宿主
    • 3
    克隆类型
    • 3
    多克隆
    标记
    • 1
    • 1
    • 1
    HRP
    应用范围
    • 2
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Cytosolic arginine sensor for mTORC1 subunit 2 protein (82-329AA)
    亚型
    IgG
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Cytosolic Arginine Sensor For mTORC1 Subunit 2 (CASTOR2)
    别名
    CASTOR2
    背景

    Background: Functions as a negative regulator of the TORC1 signaling pathway through the GATOR complex. As part of homodimers or heterodimers with CASTOR1, directly binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Does not directly bind arginine, but binding of arginine to CASTOR1 disrupts the interaction of CASTOR2-containing heterodimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.

    Aliases: CASTOR2 antibody, Cellular arginine sensor for mTORC1 protein 2 antibody, GATL2_HUMAN antibody, GATS-like protein 2 antibody, GATSL2 antibody

    UniProt
    A6NHX0
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