Cytosolic Arginine Sensor For mTORC1 Subunit 2 (CASTOR2) (AA 82-329) 抗体 (HRP)
-
- 抗原
- Cytosolic Arginine Sensor For mTORC1 Subunit 2 (CASTOR2)
- 抗原表位
- AA 82-329
- 适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- HRP
-
应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Cytosolic arginine sensor for mTORC1 subunit 2 protein (82-329AA)
- 亚型
- IgG
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- Cytosolic Arginine Sensor For mTORC1 Subunit 2 (CASTOR2)
- 别名
- CASTOR2
- 背景
-
Background: Functions as a negative regulator of the TORC1 signaling pathway through the GATOR complex. As part of homodimers or heterodimers with CASTOR1, directly binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Does not directly bind arginine, but binding of arginine to CASTOR1 disrupts the interaction of CASTOR2-containing heterodimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.
Aliases: CASTOR2 antibody, Cellular arginine sensor for mTORC1 protein 2 antibody, GATL2_HUMAN antibody, GATS-like protein 2 antibody, GATSL2 antibody
- UniProt
- A6NHX0
-