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ZNF224 抗体 (AA 206-463) (FITC)

ZNF224 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7145870
发货至: 中国
  • 抗原 See all ZNF224 抗体
    ZNF224 (Zinc Finger Protein 224 (ZNF224))
    抗原表位
    • 8
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 206-463
    适用
    • 28
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 25
    • 3
    克隆类型
    • 26
    • 2
    多克隆
    标记
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    This ZNF224 antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human BUB3-interacting and GLEBS motif-containing protein ZNF207 protein (206-463AA)
    亚型
    IgG
    Top Product
    Discover our top product ZNF224 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    ZNF224 (Zinc Finger Protein 224 (ZNF224))
    别名
    ZNF27 (ZNF224 产品)
    别名
    BMZF-2 antibody, BMZF2 antibody, KOX22 antibody, ZNF255 antibody, ZNF27 antibody, zinc finger protein 224 antibody, ZNF224 antibody
    背景

    Background: Kinetochore- and microtubule-binding protein that plays a key role in spindle assembly (PubMed:24462186, PubMed:24462187, PubMed:26388440). ZNF207/BuGZ is mainly composed of disordered low-complexity regions and undergoes phase transition or coacervation to form temperature-dependent liquid droplets. Coacervation promotes microtubule bundling and concentrates tubulin, promoting microtubule polymerization and assembly of spindle and spindle matrix by concentrating its building blocks (PubMed:26388440). Also acts as a regulator of mitotic chromosome alignment by mediating the stability and kinetochore loading of BUB3 (PubMed:24462186, PubMed:24462187). Mechanisms by which BUB3 is protected are unclear: according to a first report, ZNF207/BuGZ may act by blocking ubiquitination and proteasomal degradation of BUB3 (PubMed:24462186). According to another report, the stabilization is independent of the proteasome (PubMed:24462187).

    Aliases: Zinc finger protein 207 antibody, ZN207_HUMAN antibody, ZNF 207 antibody, ZNF207 antibody

    UniProt
    O43670
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