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Ataxin 3 抗体 (AA 1-288)

This anti-Ataxin 3 antibody is a 兔 多克隆 antibody detecting Ataxin 3 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7144793
发货至: 中国

Quick Overview for Ataxin 3 抗体 (AA 1-288) (ABIN7144793)

抗原

See all Ataxin 3 (ATXN3) 抗体
Ataxin 3 (ATXN3)

适用

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宿主

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克隆类型

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多克隆

标记

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This Ataxin 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-288

    交叉反应

    人, 小鼠

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Ataxin-3 protein (1-288AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Ataxin 3 (ATXN3)

    别名

    ATXN3

    背景

    Background: Deubiquitinating enzyme involved in protein homeostasis maintenance, transcription, cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. Binds long polyubiquitin chains and trims them, while it has weak or no activity against chains of 4 or less ubiquitins. Involved in degradation of misfolded chaperone substrates via its interaction with STUB1/CHIP: recruited to monoubiquitinated STUB1/CHIP, and restricts the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. In response to misfolded substrate ubiquitination, mediates deubiquitination of monoubiquitinated STUB1/CHIP. Interacts with key regulators of transcription and represses transcription: acts as a histone-binding protein that regulates transcription.

    Aliases: AT3 antibody, Ataxin 3 antibody, ataxin 3 variant h antibody, ataxin 3 variant m antibody, ataxin 3 variant ref antibody, Ataxin-3 antibody, ATX3 antibody, ATX3_HUMAN antibody, ATXN3 antibody, EC 3.4.22. antibody, JOS antibody, Josephin antibody, Machado Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3) antibody, Machado Joseph disease antibody, Machado Joseph disease protein 1 antibody, Machado-Joseph disease protein 1 antibody, Machado-Joseph disease protein 1 homolog antibody, MJD antibody, MJD gene antibody, MJD1 antibody, Olivopontocerebellar ataxia 3 antibody, OTTHUMP00000221583 antibody, OTTHUMP00000221585 antibody, OTTHUMP00000221586 antibody, OTTHUMP00000221587 antibody, OTTHUMP00000231995 antibody, OTTHUMP00000231997 antibody, Rsca3 antibody, SCA3 antibody, SCA3 gene antibody, Spinocerebellar ataxia type 3 protein antibody

    UniProt

    P54252
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