Ataxin 3 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for Ataxin 3 抗体 (N-Term) (ABIN2784210)
抗原
See all Ataxin 3 (ATXN3) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
原理
- ATXN3 Antibody - N-terminal region
-
序列
- SIAHQLDEEE RMRMAEGGVT SEDYRTFLQQ PSGNMDDSGF FSIQVISNAL
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 92%
-
产品特性
- This is a rabbit polyclonal antibody against ATXN3. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ATXN3
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50507-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- Ataxin 3 (ATXN3)
-
别名
- ATXN3
-
背景
-
Background Information: Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene Name: Ataxin 3
Alternative Symbols: AT3, JOS, MJD, ATX3, MJD1, SCA3
Protein Name: Ataxin-3
-
分子量
- 41kDa
-
基因ID
- 4287
-
NCBI登录号
- NP_004984
-
UniProt
- P54252
抗原
-