APAF1 抗体 (AA 104-415)
Quick Overview for APAF1 抗体 (AA 104-415) (ABIN7144485)
抗原
See all APAF1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 104-415
-
交叉反应
- 人
-
纯化方法
- >95%, Protein G purified
-
免疫原
- Recombinant Human Apoptotic protease-activating factor 1 protein (104-415AA)
-
亚型
- IgG
-
-
-
-
应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- APAF1 (Apoptotic Peptidase Activating Factor 1 (APAF1))
-
别名
- APAF1
-
背景
-
Background: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Aliases: APAF 1 antibody, Apaf-1 antibody, APAF_HUMAN antibody, Apaf1 antibody, Apoptotic peptidase activating factor 1 antibody, Apoptotic protease activating factor 1 antibody, Apoptotic protease activating factor antibody, Apoptotic protease-activating factor 1 antibody, CED 4 antibody, CED4 antibody, KIAA0413 antibody
-
UniProt
- O14727
-
途径
- p53 Pathway, Apoptosis, Caspase Cascade in Apoptosis, Tube Formation, Positive Regulation of Endopeptidase Activity
抗原
-