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Bcl-2 抗体 (AA 31-80)

This anti-Bcl-2 antibody is a 兔 多克隆 antibody detecting Bcl-2 in IHC, ELISA 和 IF. Suitable for 人.
产品编号 ABIN7144455
发货至: 中国

Quick Overview for Bcl-2 抗体 (AA 31-80) (ABIN7144455)

抗原

See all Bcl-2 (BCL2) 抗体
Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

适用

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宿主

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克隆类型

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多克隆

标记

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This Bcl-2 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
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    AA 31-80

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Apoptosis regulator Bcl-2 protein (31-80AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

    别名

    BCL2

    背景

    Background: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).

    Aliases: Apoptosis regulator Bcl 2 antibody, Apoptosis regulator Bcl-2 antibody, Apoptosis regulator Bcl2 antibody, AW986256 antibody, B cell CLL/lymphoma 2 antibody, B cell leukemia/lymphoma 2 antibody, Bcl-2 antibody, Bcl2 antibody, BCL2_HUMAN antibody, C430015F12Rik antibody, D630044D05Rik antibody, D830018M01Rik antibody, Leukemia/lymphoma, B-cell, 2 antibody, Oncogene B-cell leukemia 2 antibody, PPP1R50 antibody, Protein phosphatase 1 regulatory subunit 50 antibody, Protein phosphatase 1, regulatory subunit 50 antibody

    UniProt

    P10415

    途径

    MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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